The role of cerebral cortex in acupuncture analgesia is one of the subjects of researches on the mechanism of acupuncture analgesia. In pre- vious work we investigated the cerebral potentials evoked by pain or no- xious stimulation on normal individuals

patients undergoing cranial opera- tions and experimental animals

and observed the effect of acupuncture and some analgesics on them. The present paper is about the studies of cortical single unit activity under noxious stimulation by means of micro electrode and the effect of acupuncture on it.