针麻手术的实践以及原理研究的逐步深入

证明针刺镇痛是多种因素综合作用的结果

包括神经系统

中枢神经递质

体液因素等的参与

并起了重要的作用

但是要阐明针麻本质

提高针麻效果

不能忽视中医理论。为探索中医的辨证取穴与针麻效果的关系

应用生化指标

观察针麻胆囊切除术狗血中游离氨基酸谷氨酸(Glu)、色氨酸(Trp)

酪氨酸(Tyr)

与5-羟吲哚乙酸的变化。已知TrP为5-羟吲哚乙酸(5-HIAA)的前体氨基酸

5-HIAA为5-羟色胺(5-HT)的代谢产物

从实验资料表Expreiments were performed on 19 dogs

12 of which were operated under acupuncture anesthesia. The effects of acupuncture anesthesia were graded as; excellent (1)

good (2)

poor (3)

of these dogs 7 (58%) with excellent and 5 (41%) with poor effects in anesthesia. Serum free trypto- phan

tyrosine

glutamic acid and 5-hydroxyindolectic acid levels of 12 dogs during cholecystectomy under acupuncture anesthesia were determined by spectrophoto-fluorometric method. The results showed that the increase rate of 5-hydroxyindolectic acid in animals with excellent anesthetic effect during operation was higher than that in those with poor anesthetic effect. The increase was significant (p<0.05). It has been suggested that the change reflects one aspect of the acupu- ncture function. The change of free amino acid content in serum of dogs during chole- cystectomy under acupuncture anesthesia was not significant.