穴位处痛阈的高低与该处皮肤组织内神经成份的数量及种类究竟有无关系?穴位皮肤局部神经成份及数量与该处电针诱导后对提高全身痛阈有无关系?假若穴位局部应用交感神经化学切断剂后对穴位处痛阈有无影响?这些问题都值得探讨。材料和方法本实验共选用21只雄性大白鼠。 (一)选用雄性大白鼠6只

用WQ-PE型痛阈测量仪于安静、稳压的情况下

每次按序测量相当于“足三里”、“环跳”、“涌泉”、“劳宫”、“承浆”和“人中”等六个The relationship between the pain threshold and acetylcholinesterase(A- ChE) or cholinesterase(ChE) positive nerves in the skin at acupoints of ma- le ratswas observed by means of histochemical methods. It was found that the more the AChE positive nerves including the endings

small trunks and ne- rves surrounding the arteriole in the skin at acupoint

the lower the local pain thresholds of the acupoint (measured at the acupoint-skin). After the acupoints were electro-acupunctured for 30 minutes

although there was a marked rise of general pain threshold measured at the rats' tail

the elevated level after needling the acupoints containing more AChE-positive nerve endings was lower than that after needling those containing less nervous elements. The results may imply that to elevate the general pain threshold of the rat does not need to choose the acupoint which is rich in AChE posi- tive nerves. If the sympathetic nerves in the skin of acupoint has been in- jured by 6-OHDA

a marked decrease of local pain threshold of skin can be estimated. This indicates that the peripheral sympathetic nerve may have certain effect on the afferent conduction of painful information.