国内有些作者报道

用药物使动物血压升高时与临床治疗高血压患者相似

均表明电针足三里穴对心血管活动具有调整作用

而对正常的或氟烷浅麻醉动物均无影响。我们曾观察到

电针以乌拉坦麻醉的家兔“足三里”穴可致明显瞬间的血压下降

而且该降压效应与心率无关

也不Twentg experiments were carried on 15 rabbits. The results showed thatelectro-acupuncture of Zhusanli had very significant blood pressure loweringeffect (P<0.01) in the contrsl group of the 15 experiments (75% of the total)in 12 animals. But

as naloxone (1 to 1.5mg/kg)

the antagonist of opiate-likesubstance (OLS)

was given intravenously 5 minutes ahead of acupuncturing

the BP lowering effect weakened in varying degrees

showing no significant di-fference statically (P>0.05) in comparison with the original BP levels. In 4animals of good status

the effects of different dosage of naloxone were compa-red

and found that the weakening effect was stronger with 1.5mg/kg than 1mg/kgwith the BP measurements after application near normal or reversed. The acupu-ndture effects in percentage before and after naloxone application were signi-ficantly different (P<0.01). The above results indicate that under our presentexperimental conditions. BP lowering effect during electro-acupuncture of Zhusaliwas due to the release of OLS in the anjmal bodies with inhibitory effect onvasotension

and dilatation of peripheral arteries resulted. In the other 4 experiments (20% of the total) in 3 animals

repeated electro-acupuncture of Zhusanli were applied even with voltage augmented to 8 or 9volts

but still no significant BP lowering effect was found

and also no differe-nce happened after naloxone application

indicating no endogenous OLS wasreleased or no activation of OLS receptors took place in the animals.