In present study we observed the effect of intermittent electric acupuncture on the discharge rate of heatsensitive neurons of preoptic-anterior hypothalamus (PO-AH)in the pyrogen treated rabbit. Twenty-one rabbits

weight between 1.8-2.6 Kg

were divided into two groups at random.For group A only fourty minutes after the pyrogen being injected

electroc acupuncture was put into“Dazhui”and“Duchi”points for one minute.For group B

five minutes after the pyrogen

the electric acupu- ncture was put at the sam point for one minute

alternately with fiae minutes interval

by six times

the results were summaried as follows: 1.After the pyrogen being inlected

the average firing rate of heat-sensi- tive neurons fell 71.11 per cent.the electric acupuncture was capable of reve- rsing the pyrogen action in every experiment

generally causing discharge rate to return to the control rate. 2.The intermittent electric acupuncture could markedly block the inhibitory effect of the pyrogen on heat-sensitiue neurons in the PO-AH. The results suggest that the action of electric acupuncture as well as that of the pyrogen occur within the PO-AH area.We may imagine from this fact that there may exist a specific way of the anaganism between the electric acupuncture and pyrogeu at the cellular leve