RESEARCH ON ENERGY METABOLISM ENZYME IN LIVER OF THE RABBIT DURING HEMORRHAGIC SHOCK AND EFFECT OF ACUPUNCTURE AT "RENZHONG" ACUPOINT BY QUANTITATIVE HISTOCHEMISTRY
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RESEARCH ON ENERGY METABOLISM ENZYME IN LIVER OF THE RABBIT DURING HEMORRHAGIC SHOCK AND EFFECT OF ACUPUNCTURE AT "RENZHONG" ACUPOINT BY QUANTITATIVE HISTOCHEMISTRY
Acupuncture ResearchIssue 4, Pages: 431-434(1989)
作者机构:
中国中医研究院针灸研究所
作者简介:
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Published:1989
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RESEARCH ON ENERGY METABOLISM ENZYME IN LIVER OF THE RABBIT DURING HEMORRHAGIC SHOCK AND EFFECT OF ACUPUNCTURE AT "RENZHONG" ACUPOINT BY QUANTITATIVE HISTOCHEMISTRY[J]. Acupuncture research, 1989, (4): 431-434.
DOI:
RESEARCH ON ENERGY METABOLISM ENZYME IN LIVER OF THE RABBIT DURING HEMORRHAGIC SHOCK AND EFFECT OF ACUPUNCTURE AT "RENZHONG" ACUPOINT BY QUANTITATIVE HISTOCHEMISTRY[J]. Acupuncture research, 1989, (4): 431-434.DOI:
RESEARCH ON ENERGY METABOLISM ENZYME IN LIVER OF THE RABBIT DURING HEMORRHAGIC SHOCK AND EFFECT OF ACUPUNCTURE AT "RENZHONG" ACUPOINT BY QUANTITATIVE HISTOCHEMISTRY
摘要
休克是临床上常见的危重症
涉及医学各个学科。对于其发病机理的认识
长期以来也是学说不一
其中“细胞代谢障碍”的学说日益受到重视。多方面的研究表明
细胞在缺血缺氧时出现的能量代谢紊乱是细胞活力减低、坏死和最终各系统及脏器功能衰竭的恶性起步点。一些学者甚至提出“休克实际上是体内各器官细胞的急性The energy crisis has been considered to act a important role during shockrecent years. We all know the liver can supply for energy substrate when bodyis in an emergency condition. According to the theory of Traditional ChineseMedicine
Renzhong acupoint is a very important acu point to treat "Jue Zheng"(including shock). We divided 36 male rabbits into three groups randomly
they were normal
acupuncture and nonacupuncture. The normal control wasanesthetized only with sodium pentobarbital (35mg/kg). The acupuncture and non-acupuncture groups were operated under conscious with method of improvingwiggers(1950). After bleeding 20ml/kg
these animals were in shock. Then theacupuncture group was applied with acupuncture at "Renzhong" and the nonacup-uncture group was not during hemorrhagic shock. The samples of liver were ex-cised and stained using enzyme histochemical method. All of them were deter-mined with MPV-2 and Univar-SMSP. Two dehydrogenases (LDH and SDH) in hepatocytes were observed in this work. The results showed that the enzyme'sactivity in nonacupuncture both LDH and SDH were the weakest among threegroups (P<0.01 and P<0.05) But in acupuncture group
they were stronger than nonacupuncture group and near normal control. These suggest that acupun-cture at "Renzhong" acupoint can increase activity of LDH and SDH during hemorrhagic shock. It is useful to resistance shock in a certain degree.