By spectrophotometry we observed the changes of ChE activities in blood of 16 cases sequelitis of poliomyelitis after acupuncture treatment. (1)Before acupuncture the ChE actiuities in the plasma of 16 cases were slightly higher than the normal level. (2)After acupuncture treatment the ChE activities of the patients were marked decreased than before(P<0.01). (3)These patients were divided into two groups:acupuncture and electro- acuputicture.Among them the ChE activites of electro-acupuncture group were statically sigificant after treatment than before(P<0.05). It is suggested that after acupuncture

especially electro-acupuncture

the decrease of ChE activities lead up to the increase of Acetyl choline at the neuro-muscular junction.So transmissive function of Ach in the bodies was increased.And finally

the patients' myatrophies were improved.More studies are needed to confirm the mechanism of acupuncture treatment for sequelae of poliomyelitis.