针麻是个复杂的生理调节过程

其除了神经系统的作用外

还有体液因素的参与。近年来实验证明针刺可提高血浆中亮啡肽

ACTH

肾上腺皮质激素的含量

并且针麻效果与这些体液因素有密切关系。另有资料表明针刺可提高血浆睾酮的含量

关于睾酮水平的改变对针刺镇痛的效果是否有影响

目前尚未见报道

本文试对该问题55 rats (Wistar

Male

250-350g)were divided into 4 groups:(1)BTA (bilateral testectomy+adrenalectomy)group

(2)BT (bilateral testectomy) group

(3)BA cbilatral adrenalectomy)group

(4)SO (sham operation)group. EA was applied to bilateral “Tsusanli” points of each animal at 72h.after operation

The potassium iontophoretic dolorimetry wets used to determine the pain threshold of rats

radioimmunoassay was used to measure the contens of T and DHT in femoral vein blood

T

DHT and the pain threshold of each animal were measured before operation

at 72h

after operation and after EA

but for the SO group the measuremint was done once at 72h

after im testosterone phenylacetate.Results:The content of T in BTA and BP groups were decreased.significantly at 72h

after operation

but the changes of the pain threshold were similar to BA and SO groups

After EA the content of T in BT and SO groups were raised significantly (P<0.01)

but in BT group raised slightly (P>0.05).It was found in all animals that the content of DHT and the pain threshold were significantly elevated at 45 min after EA. No effect upon the pain threshold and EA analgesia was observed in SO group after im testosterone phenylacetate

Conclusion:T (from testes and adrenal) and DHT rose markedly after EA.Increasing T and DHT or decreasing T in plasma had no effect upon the pain threshold and EA analgesia.It is sugge- sted that T tnd DHT in plasma may not play a role in the EA analgrsia

in the other hand

EA may be used for improving the hypogonadal condition.