我们以前的工作表明

电针能明显提高因踝部注射弗氏完全佐剂引起的关节炎大鼠的痛阈

抑制其背角神经元的伤害性诱发放电

并且发现在急性佐剂性关节炎大鼠注射纳洛酮后伤害性反应明显增强

提示有中枢神经系统内源性抗痛物质的激活。那么在大鼠的行为表现上

这种内源性镇痛系The dynamic changes of the pain thresholds (Heat-WithdrawaI Latency

HWL and Stimulation-Vocalization Threshold

Voc) in the adjuvant-induced arthritic rats and the effects of EA on the pain thresholds

skin temperature and the circumference of the diseased ankle were observed. Both pain thresholds were obviously decreased in affected limbs in EA and control groups. But in the normallimbs

HWL decreased and Voc

no changed. In EA group

the ankle circumference and skin temperature were markedly lower than that in control group.The increase of the body weight was much more obvious than that in control group. Our experiment revealed that EA could not only increase the pain thresholds

but also improve the pathological changes in the inflammation of the ankle

the mechanisms of the changes of the pain thresholds and the effects of EA in the arthritic rats were discussed.