THE CORRELATION BETWEEN POSTSYNAPTIC INHIBITION AND GABA、OPIOID PIPTIDES、SP IN ELECTROACUPUNCTURE

Fang Zongren Yu Qin Li Yanhua

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THE CORRELATION BETWEEN POSTSYNAPTIC INHIBITION AND GABA、OPIOID PIPTIDES、SP IN ELECTROACUPUNCTURE

更新时间：2023-08-11

- THE CORRELATION BETWEEN POSTSYNAPTIC INHIBITION AND GABA、OPIOID PIPTIDES、SP IN ELECTROACUPUNCTURE
- Acupuncture Research Issue 1, Pages: 64-67(1993)
- 作者机构：
  
  1. 中国中医研究院针灸研究所
  2. 中国中医研究院针灸研究所,北京,100700
  3. ,北京,100700
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1993
- 稿件说明：
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Fang Zongren Yu Qin Li Yanhua. THE CORRELATION BETWEEN POSTSYNAPTIC INHIBITION AND GABA、OPIOID PIPTIDES、SP IN ELECTROACUPUNCTURE[J]. Acupuncture research, 1993, (1): 64-67.
DOI：

Fang Zongren Yu Qin Li Yanhua. THE CORRELATION BETWEEN POSTSYNAPTIC INHIBITION AND GABA、OPIOID PIPTIDES、SP IN ELECTROACUPUNCTURE[J]. Acupuncture research, 1993, (1): 64-67. DOI：

摘要

在麻醉大鼠脊髓背角神经记录投射神经元电活动

以神经元的逆向动作电位潜伏期为突触后抑制指标。电针足三里和三阴交穴使潜伏期延长0.111±0.022ms(N=12

P<0.001)。荷包牡丹碱组(N=12)电针仅延长0.010±0.04ms

与电针组有统计学差异。纳洛(?)组(N=12)和 SP 抗血清组(N=12)电针使潜伏期发生有意义的变化。实验表明 r-氨基丁酸

阿片肽和 P 物质可能参与电针的突触后抑制效应。

Abstract

Identified tract cells in lumbar enlargement were recorded from intact ana-esthetized rats.The prolongation of the latency of antidromic action potentialwas a measure of postsynaptic inhibitipn.Both ST 36 and SP 6 were stimulatedelectrically.In EA group (N=12) EA prolonged the latency for 0.111±0.022ms(P<0.001).In bicuculline group (N=12) the prolongation of the latency for0.010±0.004ms (P<0.05) by EA was less than that of EA group with stati-stical significance.In naloxone group (N=12) and SP antiserum group (N=12)EA did not induce a significant prolongation of the latency.It suggested thatGABA

opioides and SP might be involved in postsynaptic inhibition induced byEA.

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Related Institution

Department of Gastroenterology, Tangdu Hospital Affiliated to the Fourth Military Medical University

~1Institute of Neuroscience, the Fourth Military Medical University

Institute of Acu-moxibustion, China Academy of Chinese Medical Sciences

中国中医科学院针灸研究所

Center for Social Studies of Science,Peking University

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