The experiment was designed to study the effects of acupuncture hypothermia and its relationship to the changes of arginine vasopressin (AVP) contents in the plasma and cerebrospinal fluid (CSF)of the rabbits. The results were as follows: (1)The intermittent electroacpuncture obviously inhibits the fever induced by endotoxin in rabbits

AVP contents in the plasma and CSF were increased markedly in comparison with normal and febrile rabbits. (2) Injection of AVP-antiserum into the septal area markedly reduced effects of acupuncture hypothermia. The experimental resuhs suggested that one of the mechanisms of acupuncture hypothermia might be promoting release of endogenous AVP.