Observation was made on the effect of different acupuncture manipulation on plasma estradiol(E2)

testoserone(T)

E2/T and cortisol(C)in 78 patients with kidney dificiency.The resultsshowed that the level of E2 and T in women was lowered by both reinforcing manipuhtion(RFM)and reducing manipulation(RDM).E2/T index was lowered by RDM but not by RFM

and therewas significance(P<0.05)between the RDM group and RDM group in E2/T

but no significancebetween the man's groups.The level of C was decreased by RDM but not by RFM.The results sug-gest that the different manipuldation effects are different on the level of sex hormones in women andthe C content in patients with kidney dificiency.