Clinical subjects were the patients in whom cholecystectomy and choledochotorny were performedwith T tube drainage. Four groups of acupoints were established according to different point prescriptions. Under the strict control of experimental conditions and fixation of electrical acupuncture stimulation parameters- the changes of hepatic bile output were observed in five different stages before.during and after acupuncture

and compared with those in control group not treated by acupuncture.The results showed that electrical acupuncture of Ganshu (Back Shu point ) (GB 18 ) and Qimen(Front-Mu point ) (LI 14 )could obviously promote the secretion of hepatic bile. The immediate effectwas superior to that in other groups. ln a group not treated by acupuncture - hepatic bile output gradually decreased as time went on.In animal experiment. a rnodel of bile pigrnent lithogenesis was rnade in gulnea plg. The' animalswere randomly divided into five groups of control

sirnultaneous acupuncture' simultaneous moxihustion

re-acupuncture after one week and re-acupuncture after two weeks. The results indicated thatelectrical acupuncture or moxibustion of relevant acupoints such as Ganshu (GB 18) and Qimen (LI14 ) could really very effectively inhihit the animal lithogenesis caused by lithogenous food. A tendencywas observed towards that the earller acupuncture was perforrned

the better the preventive effect onlithogenesis. In the influence on lithogenous bile

both acupuncture and moxibustion could reduce thecontents of biliary total bilirubin and free bilirubin and the activity of hiliary 8-glycuronidase.Acupuncture also produced an effect in lowering hepatic 8-glycurouidase but moxibustion didh't. Hepatohistological observation showed that lithogenous food could also cause fatty degeneration of Iiver.and moxlbustion could markedly inhibit its progress. Both acupuncture and rnoxibustion didn't remarkably infIuence the content of serurn cholesterol.