The expcrimental rats were randomly divided into three groups: L e. controI group; endotoxicshock group (the model of endotoxic shock was induced by intravenous administration of E. Coli endotoxin

16mg/kg ): and electroacupuncture (EA ) group (" Renzhong" or ' Zusanli)' acupolnt wasstirnulated for 1o minutes at l hr after injection of endotoxin)- The experimental rats were decapitated at 75 minutes after injccting endotoxin. Their livers were taken out for cryostat section - and histo-chemical observation. The results were as follows: 1 ) The glycogen in the hepatic cells of endotoxicshocked rats were alrnost completely depleted- The activities of SDH Mg++u ATPase. G-6-Pase and5'

N

ase were decreased: especially the activities of 5'-Nase 1n the biliary canallcull and sinusoids wereapparently rec1uced. 2 ) The content of hepatic glycogen in EA group was increased

but some of themwas still dePleted. The activities of SDH

Mg++-ATPase and G-6-Pase were slightly increased ascompared wlth that of the endotoxic shock group. The activity of 5'uNase was obviously increased afte r EA. The prelin1inary results indicated that EA at "Renzhong" or IlZusanliI' acupoint of rats withndotoxic shock mlght play certain role on lmproving the hepatic metabolism and prornoting the rnembrane transport action