Influence of EA and ACh on Nociceptive Responses of Pf Neurons Following Topical Application of HC-3 at SmI in Rats

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Influence of EA and ACh on Nociceptive Responses of Pf Neurons Following Topical Application of HC-3 at SmI in Rats

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- Influence of EA and ACh on Nociceptive Responses of Pf Neurons Following Topical Application of HC-3 at SmI in Rats
- Acupuncture Research Issue 4, Pages: 30-33(1995)
- 作者机构：
  
  中国中医研究院针灸所,北京,100700
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1995
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Influence of EA and ACh on Nociceptive Responses of Pf Neurons Following Topical Application of HC-3 at SmI in Rats[J]. Acupuncture research, 1995, (4): 30-33.
DOI：

Influence of EA and ACh on Nociceptive Responses of Pf Neurons Following Topical Application of HC-3 at SmI in Rats[J]. Acupuncture research, 1995, (4): 30-33. DOI：

摘要

本实验用玻璃微电极细胞外记录和微电泳的方法，观察到：电针“足三里”、“环跳”穴能够抑制丘脑束旁核（Pf）神经元的伤害性反应；用密胆碱（HC－3）处理大鼠皮层SmI后，电针的抑制作用被取消；微电泳外源性导入乙酰胆碱（ACh）后，丘脑Pf神经元的伤害性反应被抑制，此作用与HC－3处理SmI前的电针效应相似。由此提示：电针可通过激活大鼠皮层SmI释放ACh，抑制丘脑Pf神经元的伤害性反应。

Abstract

The influences of EA and iontophoretic ACh on nociceptive responses of Pf neurons following topical application of HC-3 at Sml were recorded extracellularly by multi-microelectrodes in rats. It was found that EA could inhibit the nociceptive responses of Pf neurons; the inhibition could be eliminated by topical application of HC-3 at SmI; iontophoretic ACh could also induce the inhibition

which was similar to the effect of EA obtained before HC-3 application at SmI. The results indicate that EA can inhibit the nociceptive responses of Pf neurons through SmI releasing ACh.

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Influence of SmI Lesion on Acupuncture-Induced Analgesia in Thalamic Pf Neurons and Effects of Iontophoretic Ach on Their Nociceptive Responses

Related Author

徐维

徐志卿

徐维

陈正秋

China)

Beijing 100700

China Academy of Traditional Chinese Medicine

Chen Zhengqiu Zheng Xin Shi Hong Xu Wei Institute of Acupuncture

Related Institution

Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine

中国中医研究院针灸研究所

同济医科大学基础医学院生理学教研室

Dept. of Physiol., Tongji Medical Univ.

Department of Neurobiology, Tongji Medical University

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