The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain
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The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain
Acupuncture ResearchIssue 1, Pages: 52-55(1996)
作者机构:
1. 上海医科大学神经生物教研组,上海,200032
2. 上海华东医院
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Published:1996
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The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain[J]. Acupuncture research, 1996, (1): 52-55.
DOI:
The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain[J]. Acupuncture research, 1996, (1): 52-55.DOI:
The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain
can inhibit electroacupuncture-induced analgesia (EAA) for 15 min
with its biggest effect reducing the pain threshold of electroacupuncture (EA) to the level of sham electroacupuncture (SEA). Yohmbine also completely inhibit the increase of 3-endorphin in the push-pull liquids from ventriculus lateralis cerebri caused by EA. But yohirnbine itself produce no effect on pain threshold and the concentration of 3-endorphin. These results suggest that EAA and the increased release of β-endorphin caused by EA are related to the activation of α2-adrenergic receptor in the spinal cord