The function of red nucleus (RN) was important in motor control. This work was to study whether the RN influenced the effect of EA and the somatosensory afferent system. C-responses of spinal dorsal horn neurons(SDHN) were recorded as nociceptive responses- Electrical stimulation of RN could intensify the inhibitory effect of EA and inhibit nociptive reponse of SDHN. Naloxone(NX) could completely block that inhibition of RN- The result inferred that the RN can modulate both of somatomotion and somatosense. The endogenous opiate system is involved in the somatosensory modulation of RN