Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats

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Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats

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- Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats
- Acupuncture Research Issue 1, Pages: 36-40(1998)
- 作者机构：
  
  上海医科大学医学神经生物学国家重点实验室,上海,200032
- 作者简介：
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- Published：1998
- 稿件说明：
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Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats[J]. Acupuncture research, 1998, (1): 36-40.
DOI：

Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats[J]. Acupuncture research, 1998, (1): 36-40. DOI：

摘要

本实验在大脑中动脉阻塞（MCAO）及再灌注动物模型上，观察缺血后电针对大鼠体感诱发电位（SEP）和脑梗塞体积的影响。结果发现缺血组和缺血后电针组在MCAO后30分钟，缺血侧SEP波幅降至缺血前的2．2±3％，1．9±2％，缺血后再灌注7天，SEP恢复至缺血前的25．5±14．1％，58．6±27．2％，两组比较P＜0．05；脑梗塞体积分别为70．72±25．4mm3，45．65±11．4mm3（P＜0．05）。结果提示电针可促进脑缺血后SEP的恢复，减少脑缺血性组织坏死。

Abstract

The model of reversible middle cerebral artery occlusion(MCAO) was used to study the effect of electroacupuncture(EA) on somatosensory evoked potential (SEP) and infarct volume after MCAO in rats. After 1 hour of MCAO

EA was applied at the points of Fengfu(DU 16)and Renzhong(DU 26).The results were as follows: (1) In MCAO group and MCAO + EA group the amplitude of SEP on the ipsilateral side of MCAO was nearly abolished at 30 min after MCAO and recovered to 25.5±14.1%

58. 6±27. 2 % (P <0.05)on day 7 after reperfusion. (2) The infarct volume in MCAO group and EA + MCAO group was 70. 72±25. 4mm3

45. 65±11. 4mm3 (P <0.05) respectively after reperfusion 7 days following MCAO 2 hours.The results above indicate that EA might produce cerebroprotective effect after focal cerebral ischemia.

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Related Institution

Institute of Acupuncture Research, National Key Laboratory of Medical Neurobiology, Medical Center of Fudan University

复旦大学医学院针刺原理研究所医学神经生物学国家重点实验室

医学神经生物学国家重点实验室

Department of Physiology, Chongqing University of Medical Sciences

Guangzhou University of TCM

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