In the present study

effects of pricking blood at the "twelve-well points of the hand" ("pricking blood" in abbreviation)

pricking blood plus intravenous injection of morphine

intravenous injection of morphine and painful stimulation (by clamping the skin of the bilateral upper limbs on the back side with a pair of hemostatic forceps) on the amplitude of rheoencephalogram (REG) were observed in rabbits with experimental cerebral ischemia. Results showed that painful stimulation induced by pricking blood at the "twelve-well points" of upper paws played a principal role on the amplitude of REG but was definitely not a sole factor.