The author observed the blood cholesterol day and night variation of the normal rabbit and experimental hyperlipemia rabbit

and the effect of electroacupuncture at Zusanli(ST 36) at different time on hyperlipemia. The results show:① There is a circadian rhythm in normal rabbit's blood cholesterol. The peak value appears during 21

23 hours (Hai-time)

and the valley value appears during 11 23 hours (Hai-time)

and the valley value appears during 11

13 hours (Wu-time). The circadian rhythm disappears in rabbits with hyperlipemia. ②The therapeutic effect of electroacupuncture at Zusanli on hyperlipemia is better at Hai-time.