Objective: To observe the effect of acupoint stimulation on the internal organs under experimental dorsal root reflex and axonal reflex. Methods: 29 SD rats were randomly divided into control group (n=8)

experimental group (n=13) and casaicin group (n=8). A transverse incision operation of spinal cord between T 12 and T 13 was performed in these rats and all the ventral roots below T 13 were amputated. Evans fluid (40 mg/kg) was injected intravenously via the external jugular vein. Left "Zusanli"(ST 36) was stimulated electrically for 30 min with a concentric electrode by setting the stimulating parameters of wave width being 0.5 ms

strength 15 mA and frequency 5 Hz. Rats of capsaicin group were treated by injecting capsaicin 50 μL(66 mMol) into "Zusanli"(ST 36) 6 days before each experiment for injuring fine afferent nerve fibers. At the end of each experiment

the rats were killed for opening the abdominal cavity and observing exudation state in the internal organs. The neurogenic inflammation was considered to be the index of the activity of meridian. Results: Findings showed that under the two reflex conditions

the Evans blue content of the visceral organs such as liver

spleen

pancreas and the whole gastrointestinal tract increased significantly compared with that of control group(P<0.01) following electrical stimulation of "Zusanli"(ST 36). The exudation was not evident in the lung

heart

bladder

kidney

ureter

spermatic duct

testicle

etc. No significant differences were found between experimental group and control group in Evans blue content in bladder

testicle

etc. The present study provided a new way to study the correlation between meridian and visceral organs. In capsaicin group

no significant differences were found between capsaicin and control group in the Evans blue contents in these organ tissues (P>0.05)

but in comparison with experimental group

Evans blue contents in liver

spleen

pancreas and gastrointestinal tract lowered apparently (P<0.01). Conclusion: The fact suggests that the neurogenic inflammation of the viseral organs evoked by electrical stimulation of acupoint is mediated by the capsaicin sensitive afferent fibres.