Objective: To observe the effect of electroacupuncture(EA) on the learning and memory ability in diabetic cognitive dysfunction patients.Methods: Forty-five cases of diabetic mellitus(DM) patients with cognitive dysfunction were randomly divided into EA group(n=25) and medication group(n=20).For patients of EA group
main acupoints as Sishenchong(EX-HN 1)
Baihui(GV 20)
bilateral Fengchi(GB 20)
Benshen(GB 13) and Neiguan(PC 6) were punctured with filiform needles and stimulated electrically by setting the stimulating parameters being dense-sparse waves
frequency of 14-26 pulses/min
strength of 3-(5 mA) and duration of (30 min).The treatment was conducted once daily
5 times a week and continuously for 6 weeks.Patients of medication group were ordered to take Nimotop((30 mg)/time)
3 times everyday and continuously for 6 weeks.Modified Hastgawa Dementia Scale(HDS) and Wilson's Memory Scale(WMS) were used to evaluate the patients' cognitive function
memory ability and general conditions before and after the treatment.Results: After the treatment
according to HDS
of the 20 and 25 cases in medication and EA groups
1(5%) and 4(16%) experienced marked improvement
5(25%) and 15(60%) had moderate improvement
10(50%)and 5(20%) had mild improvement
and 4(20%) and 1(4%) had no improvement
with the total effective rates being 80% and 96% respectively.Rank test showed that the therapeutic effect of EA group was significantly superior to that of medication group(P<0.05) in improving patients' cognitive function.Self-comparison indicated that WMS of both groups increased significantly after the treatment(P<0.001
0.05)
including adding test of long-term memory and touching test of short-term memory in medication group
counting-down test of long-term memory
association test and touching test of short-term memory in EA group;and the effects of EA were apparently superior to those of medication in raising WMS(MQ)
counting-down test and association test(P<0.05
0.01).Conclusion: The therapeutic effect of EA is significantly superior to that of Nimotop in improving DM patients' cognitive function
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Related Author
赖新生
王黎
PAN You-can
XU Neng-gui
YI Wei
SHI Jun-heng
ZHENG Xiao-yan
ZHANG Hui-zhen
Related Institution
Guangzhou University of TCM
广州中医药大学
Southern China Research Center for Acupuncture and Moxibustion,Guangzhou University of Traditional Chinese Medicine