Effects of Electroacupuncture on Sucrose Intake and Sexual Behavior in Depression Rats and Its Related Mechanism
|更新时间:2023-08-11
|
Effects of Electroacupuncture on Sucrose Intake and Sexual Behavior in Depression Rats and Its Related Mechanism
Acupuncture ResearchIssue 1, Pages: 27-30(2006)
作者机构:
北京中医药大学针灸学院
作者简介:
基金信息:
DOI:
CLC:
Published:2006
稿件说明:
移动端阅览
SHI Yu-jing, LU Jun, JIA Bao-hui, et al. Effects of Electroacupuncture on Sucrose Intake and Sexual Behavior in Depression Rats and Its Related Mechanism[J]. Acupuncture research, 2006, (1): 27-30.
DOI:
SHI Yu-jing, LU Jun, JIA Bao-hui, et al. Effects of Electroacupuncture on Sucrose Intake and Sexual Behavior in Depression Rats and Its Related Mechanism[J]. Acupuncture research, 2006, (1): 27-30.DOI:
Effects of Electroacupuncture on Sucrose Intake and Sexual Behavior in Depression Rats and Its Related Mechanism
Objective: To investigate the effect of electroacupuncture(EA) on the natural reward behavior and the related mechanism in depression rats.Methods: Thirty male SD rats were evenly randomized into control
model and EA groups.Depression model was established by using chronic stress stimulation including forced cool water swim
tail-clamping
fasting
electric shock
etc.
once daily
(21 days) altogether.One hour before stress stimulation in EA group
EA((2 Hz)
(2 mA)) was applied to "Baihui"(GV 20) and "Yintang"(EX-HN 3) for(20 min)
once daily
continuously for 21 days.The consumption of the rats' sucrose intake was detected before and after establishment of depression model.The rat's sexual behavior was recorded by calculating the times of mounting the female rat and sniffing female rat's pudendum in 15 minutes.Dopamine(DA) contents of frontal cortex
striate body and hypothalamus tissues were assayed by using high performance liquid chromatography electro-chemical detection technique.Results: Compared with control group
the male rats' sucrose intake amount
pudendum-sniffing times
DA contents of frontal cortex
striate body and hypothalamus tissues in model group decreased significantly(P<0.05
0.01);while compared with model group
the rats' sucrose intake amount
mounting and sniffing times and DA contents of the aforementioned 3 cerebral areas in EA group increased significantly(P<0.05).No significant differences were found between control and EA groups in sucrose intake amount
pudendum-sniffing times and DA contents of the 3 cerebral areas(P>0.05).Conclusion: EA can promote recovery of the rats' food rewarding and sexual reward and adjust the secretion of DA in depression rats.