This article briefly reviews the general understanding of endogenous neural stem cells(eNSCs) in the CNS over the past 50 years.The proliferation and differentiation of neural progenitors continue throughout the lifetime

instead of cell division stopping at the postnatal period.In the spinal cord

these cells differentiate into different kinds of glial cells.Based on his current research in spinal cord injury(SCI)

the author reports that the implantation of functional electrical stimulation(FES) in the motor cortex or the peripheral nerve increases cell birth and differentiation of eNSCs in the spinal cord.Furthermore

electrical stimulation promotes remyelination and neural repair.Finally

this article discusses the possibility of the application of eNSCs and FES in electroacupuncture research.