Effect of Electroacupuncture and Moxibustion of "Dazhui"(GV 14) on the Number and Distribution of Degranulated Mast Cells in GV14 Region

LUO Ming-fu; HE Jun-na; GUO Ying; LI Cui-hong; ZHANG Jin-ling

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Effect of Electroacupuncture and Moxibustion of "Dazhui"(GV 14) on the Number and Distribution of Degranulated Mast Cells in GV14 Region

更新时间：2023-08-11

- Effect of Electroacupuncture and Moxibustion of "Dazhui"(GV 14) on the Number and Distribution of Degranulated Mast Cells in GV14 Region
- Acupuncture Research Issue 5, Pages: 327-329(2007)
- 作者机构：
  
  中国中医科学院针灸研究所
- 作者简介：
- 基金信息：
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- Published：2007
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LUO Ming-fu, HE Jun-na, GUO Ying, et al. Effect of Electroacupuncture and Moxibustion of "Dazhui"(GV 14) on the Number and Distribution of Degranulated Mast Cells in GV14 Region[J]. Acupuncture research, 2007, (5): 327-329.
DOI：

LUO Ming-fu, HE Jun-na, GUO Ying, et al. Effect of Electroacupuncture and Moxibustion of "Dazhui"(GV 14) on the Number and Distribution of Degranulated Mast Cells in GV14 Region[J]. Acupuncture research, 2007, (5): 327-329. DOI：

摘要

目的:观察电针和悬灸对大鼠穴区肥大细胞(mast cells

MCs)分布和脱颗粒的不同影响

以探索针灸治病的机制。方法:正常成年Wistar大鼠15只

分为对照组、电针组和悬灸组。电针(疏密波

频率3

0 Hz

电压210 Hz

电压2

V)或悬灸(2壮)"大椎"穴20 min后

取"大椎"穴区组织恒冷箱切片

甲苯胺兰染色

显示皮肤、皮下组织和肌肉组织内MCs的分布、数量和脱颗粒情况。结果:在穴区组织内

从真皮至皮下组织、肌肉组织均可见MCs存在和脱颗粒发生。悬灸刺激的"大椎"穴区的组织切面中心部位

从皮肤表面至皮下组织内MCs数量很少

但中心周边的MCs数量多

脱颗粒明显。悬灸组发生脱颗粒的MCs数量明显多于对照组和电针组

电针组脱颗粒细胞明显多于对照组

差异均有显著性意义(P

0.05

0.01)。结论:电针和悬灸对穴区组织内MCs的数量、分布以及细胞的脱颗粒的影响明显不同

艾灸对MCs脱颗粒的影响强于电针。

Abstract

Objective: To compare the effects of electroacupuncture(EA) and moxibustion on the degranulated mast cell number and distribution in "Dazhui"(GV 14) region of rats.Methods: Fifteen Wistar rats were randomly divided into normal control

EA and moxibustion groups

with 5 cases in each group."Dazhui"(GV 14) was stimulated by EA(3/10 Hz

2-4 V

20 min) or moxibustion(2 cones

20 min)

thereafter

the tissues of GV14 region were sampled

quickly frozen

sectioned(20 μm) and stained with toluidine blue separately for observing the degranulated state of mast cells under microscope.Results: The mast cells(MCs) distributed widely in GV14 region from the dermis

subcutaneous tissue to muscle layer.Compared with control group

MCs of moxibustion group were significantly fewer in the number(P<0.05)

and those degranulated MCs in both EA and moxibustion groups were evidently more in the number(P<0.01)

and the number and percentage of the degranulated MCs in moxibustion group were significantly more than those of EA group(P<0.05)

suggesting that EA and moxibustion could promote the release of granules of mast cells in the stimulated acupoint region

and the effect of moxibustion is stronger.Conclusion: Both EA and moxibustion can promote the degranulation of MCs

and the effect of moxibustion is markedly stronger in potentiating the release of granules from MCs in GV14 in rats.

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Related Institution

中国中医科学院针灸研究所

College of Acupuncture and Tuina,Liaoning University of Traditional Chinese medicine

College of Traditional Chinese Medicine,Liaoning University of Traditional Chinese medicine

College of Acupuncture-moxibustion and Massage,Hunan University of Traditional Chinese Medicine

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