Effect of Nitric Oxide on Noradrenergic Function and Skin Electric Resistance of Acupoints and Meridians

LIANG Yuan; MA Sheng-xing1; CHEN Jia-xu

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Effect of Nitric Oxide on Noradrenergic Function and Skin Electric Resistance of Acupoints and Meridians

更新时间：2023-08-11

- Effect of Nitric Oxide on Noradrenergic Function and Skin Electric Resistance of Acupoints and Meridians
- Acupuncture Research Issue 3, Pages: 213-216(2008)
- 作者机构：
  
  1. 北京中医药大学基础医学院
  2. 美国加利福尼亚大学洛杉矶分校
- 作者简介：
- 基金信息：
- DOI：
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- Published：2008
- 稿件说明：
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LIANG Yuan, MA Sheng-xing1, CHEN Jia-xu. Effect of Nitric Oxide on Noradrenergic Function and Skin Electric Resistance of Acupoints and Meridians[J]. Acupuncture research, 2008, (3): 213-216.
DOI：

LIANG Yuan, MA Sheng-xing1, CHEN Jia-xu. Effect of Nitric Oxide on Noradrenergic Function and Skin Electric Resistance of Acupoints and Meridians[J]. Acupuncture research, 2008, (3): 213-216. DOI：

摘要

经脉/穴位具有皮肤低电阻特性。我们进行了3次实验

结果证明:经脉区皮肤组织的一氧化氮(NO)含量和神经一氧化氮合酶(nNOS)蛋白表达较高

外源性NO和nNOS抑制剂能够调节穴位皮肤中去甲肾上腺素(NE)的合成与释放

L-精氨酸衍生的NO复合物和NE可以调节皮肤低电阻穴位的皮肤电导。说明经穴的皮肤低电阻特性可能与NO和NE有关。

Abstract

Most acupuncture points correspond to low skin-resistance points(LSRP) on the body surface along the meridians.We did three experiments which conformed that the skin nitric oxide(NO) concentration and expression of neuronal nitric oxide synthesis(nNOS) were higher than those in non-acupoints

and non-meridian control points.Noradrenaline(NE) synthesis/release was modulated by exogenous NO donor and selective inhibitor of nNOS in the skin acupoints/meridians.Skin electrical currents in low skin resistance points were modified by L-arginine-derived NO synthesis and NE.As a conclusion

NO-NE contribute to low resistance characteristics of acupoints and meridians.

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Related Institution

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