Ever since 1964

we have carried out experimental and clinical researchesto study the mechanism of acupuncture analgesia(AA) using multidisciplinarytechniques of neurophysiology

neuropharmacology

neuromorphology and neuro-biochemistry. It was found that afferent impulses arising from the acupuncturepoints travel along the neuropathway of the pain and temperature sensation(ventrolateral funiculi) of the spinal cord

reach the brain and activate thepain modulating system including some brain areas of limbic system to bringabout neurobumoral interaction among endogenous opioid peptides and differentneurotransmitters to activate the descending inhibitory system thus resulting inanalgesia. The main results are as follows.