Objective To observe the effect of electroacupuncture(EA) of different acupoint groups on mean arterial pressure(MAP) and heart rate variability(HRV)in hypotension rats.Methods A total of 70 Wistar female rats were randomized into model

"Neiguan"(PC 6)-"Daling"(PC 7)

"Waiguan"(SJ 4)-"Yangchi"(SJ 5)

"Tianshu"(ST 25)-"Wailing"(ST 26)

"Dachangshu"(BL 25)-"Qihaishu"(BL 24)

"Baihui"(GV 20)-"Qianshencong"(EX-HN)

and"Guangming"(GB 37)-"Xuanzhong"(GB 39)groups

with 10 cases in each.Hypotension model was established by bleeding(2.5-3 ml) through carotid artery.Immediately after bleeding

EA(2/15 Hz

1 mA

30 min) was applied to the above-mentioned acupoints of the 6 EA groups.MAP and ECG were recorded

then HRV was analyzed by using software Chart 5.2.1.Results MAP declined significantly after bleeding.Compared with model group

MAP values of PC6-PC7 and GB37-GB39 groups increased significantly 15 min and 30 min after bleeding

and those of ST25-ST26 and GV20-EX-HN groups also increased apparently 30 min after bleeding(P<0.05).No marked effects were observed in EA of SJ4-SJ5 and BL25-BL24 groups(P>0.05).The effect of PC6-PC7 and GB37-GB39 groups was significantly superior to that of SJ4-SJ5

BL25-BL24 and GV20-EX-HN groups in elevating MAP 30 min after bleeding(P<0.05).Compared with model group

heart rate(HR) of PC6-PC7 group was increased significantly 15 min and 30 min after bleeding(P<0.05.).After bleeding

low frequency(LF)

LF/high frequency(HF) and very low frequency(VLF) increased apparently.Compared with model group

LF

LF/HF and VLF of PC6-PC7 and GB37-GB39 groups decreased significantly 30 min after bleeding(P<0.05)

suggesting a better balancing effect of EA of PC6-PC7 and GB37-GB39 on the activities of sympathetic and vagus nerves.Conclusion EA of different acupoint groups has its own relative specificity in regulating MAP and HR in the rat

and PC6-PC7 EA and GB37-GB39 EA have a better efficacy

which is closely associated with their effects in balancing activities of the autonomic nerve system.