The clinical and experimental researches of acupuncture and moxibustion on endometriosis during past 15 years were collected. The research progress underling the mechanism of acupuncture and moxibustion on endometriosis was summarized. By taken Chinese characters

i.e."acupuncture-moxibustion"and"endometriosis"as well as the English words

i.e."acupuncture therapy"and"endometriosis"as the searching words

the relevant articles were retrieved from Pubmed

Embase

Chinese China National Knowledge Infrastructure

Wanfang Database

Chongqing VIP and the China Biology Medicine Disc etc. The retrieval time was from January 2003 to October 2018. As a result

41 articles of clinical studies and 18 articles of animal experiments were screened. Of them

20 articles(including 18 articles of animal experiments and 2 articles of clinical trial)are related to the mechanism underling acupuncture and moxibustion on endometriosis. In term of the impacts on growth factors

enzymes and enzyme inhibitors

the mechanism of acupuncture and moxibustion was explored on the analgesia for endometriosis

the inhibition of ectopic tissue angiogenesis and invasive adhesion

as well as the regulation of immune function and endocrine. Moreover

the limitation and prospect on the current researches were proposed so as to provide the more reliable evidence for clinical treatment of endometriosis with acupuncture and moxibustion.