Effects of Electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on Cardiac Function in Acute Myocardial Ischemia Rabbits

CAI Rong-lin; HU Ling; WANG Ke-ming; WU Zi-jian; CHEN Ye-nong; LONG Di-he; HE Lu; LIU Jing; ZHOU Yi-ping

doi:10.13702/j.1000-0607.2010.02.004

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Effects of Electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on Cardiac Function in Acute Myocardial Ischemia Rabbits

更新时间：2023-08-11

- Effects of Electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on Cardiac Function in Acute Myocardial Ischemia Rabbits
- Acupuncture Research Vol. 35, Issue 2, Pages: 104-107(2010)
- 作者机构：
  
  安徽中医学院针灸经络研究所针灸基础与技术安徽省重点实验室培育基地
- 作者简介：
- 基金信息：
- DOI：10.13702/j.1000-0607.2010.02.004
  CLC：
- Published：2010
- 稿件说明：
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CAI Rong-lin, HU Ling, WANG Ke-ming, et al. Effects of Electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on Cardiac Function in Acute Myocardial Ischemia Rabbits[J]. Acupuncture research, 2010, 35(2): 104-107.
DOI：

CAI Rong-lin, HU Ling, WANG Ke-ming, et al. Effects of Electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on Cardiac Function in Acute Myocardial Ischemia Rabbits[J]. Acupuncture research, 2010, 35(2): 104-107. DOI： 10.13702/j.1000-0607.2010.02.004.

摘要

目的:研究电针"内关""太冲"穴对急性心肌缺血家兔心功能的影响

比较同名经原穴间的效应差异。方法:健康青紫蓝家兔50只

随机选择8只作为正常组

余经股静脉注射垂体后叶素造急性心肌缺血模型。将造模成功的家兔随机分为模型组、"内关"组、"太冲"组和非经穴组

每组8只。观察电针前后各组家兔心功能变化情况。结果:"内关"组及"太冲"组家兔的室内压上升段最大变化率(+dp/dt max)、室内压下降段最大变化率(-dp/dt max)与模型组比较显著升高(P<0.01)。"内关"组的左心室收缩压力峰值(LVSP)与模型组比较显著升高(P<0.05)

电针"太冲"穴对LVSP的调节作用不显著(P>0.05)。非经穴组的+dp/dt max、-dp/dt max及LVSP与正常组比较明显降低(P<0.01)

与模型组比较差异无统计学意义(P>0.05)。结论:电针"内关""太冲"穴对急性心肌缺血家兔的心功能均有一定的改善作用

且心包经的络穴"内关"对心脏功能的调节作用优于其同名经的原穴"太冲"。

Abstract

Objective To observe the effect of electroacupuncture(EA) of "Neiguan"(PC 6) and "Taichong"(LR 3) on mechnical activities of the heart in acute myocardial ischemia(AMI) rabbits.Methods Fifty chinchilla rabbits were randomized into normal control

model

EA-PC 6

EA-LR 3 and non-acupoint groups(n=8/group).AMI model was duplicated by intravenous injection(femoral vein) of posterior pituitrin(3 U/kg).The maximal ascending velocity(+dp/dt max)

maximal descending velocity(-dp/dt max) and left ventricular systolic pressure(LVSP) of the heart were recorded by using Biopac Bio-signal system.EA(1 mA

2 Hz) was applied to PC 6

LR 3 and non-acupoint for 10 min.Results Compared with normal control group

+dp/dt max

-dp/dt max and LVSP of the heart in model group reduced significantly(P<0.01);while in comparison with model group

left ventricular +dp/dt max and-dp/dt max at 10 min after EA in EA-PC 6 and EA-LR 3 groups increased markedly(P<0.01)

and LVSP of EA-PC 6 group increased remarkably(P<0.05).No significant differences were found between EA-non-acupoint group and model group in the above-mentioned 3 indexes(P>0.05).Conclusion Both EA of PC 6 and LR 3 points can improve AMI induced reduction of the left ventricular myocardial mechanical activities in the rabbit

and the therapeutic effect of EA-PC 6 is superior to that of EA-LR 3.

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