Objective To observe the therapeutic effect of acupuncture therapy for aura-absence migraine.Methods A total of 60 aura-absence migraine outpatients who signed an informed consent participated in the present study.They were randomized into medication group and acupuncture group(n=30/group) according to a randomized number table and their visiting sequence.Patients of acupuncture group were treated by acupuncture of Ashi-point
Baihui(GV20)
Taiyang(EX-HN5)
Shuaigu(GB8)
Fengchi(GB20)
Benshen(GB13) and Lieque(LU7).The acupuncture needles were retained for 30min after "Deqi"
and the treatment was conducted once daily
6 times every week and continuously for 4 weeks.Patients of the medication group were treated with oral administration of Flunarizine(10mg/time
once every night) for 4 weeks.The SF-36 Quality-of-Life Instrument(SF-36) and integral scores of headache were measured before and after the treatment.Results In comparison with the pre-treatment
scores of physical functioning(PF)
role-physical(RP)
bodily pain(BP)
social functioning(SF)
role-emotional(RE)
vitality(VT)
mental-health(MH) and general health(GH) of SF-36 in both medication and acupuncture groups were increased significantly(P<0.05)
and those of PF
RP and BP of the acupuncture group were significantly higher than the scores of the medication group(P<0.05).The integral scores of headache were decreased significantly in both medication group and acupuncture group(P<0.05)
and those of the acupuncture group were remarkably lower than the scores of the medication group after the treatment(P<0.05).Of the two 30 migraine patients in the medication and acupuncture groups
1(3.33%) and 9(30.00%) were cured
1(3.33%) and 2(6.67%) had a marked improvement in their symptoms
9(30.00%) and 8(26.67%) were effective
19(63.33%) and 11(36.67%) were ineffective
with the total effective rates being 36.67% and 63.33%
respectively.The cure rate and the total effective rate of the acupuncture group were significantly higher than those of the medication group(P<0.05).Conclusion Acupuncture therapy can raise the migraineurs' life quality
lessen the times and severity of headache attack
and its therapeutic effect is superior to that of medication.
Acupuncture relieves pain by inhibiting expression of Cx43 in astrocytes and release of interfe-ron-γ in neurons of trigeminal spinal nucleus in rats with migraine
Manual Acupuncture Stimulation Regulates Expression of Receptor Activity-modifying Protein 1 and 5-HT 1D Receptor Proteins and Genes in Migraine Rats
Research progress on the mechanism of acupuncture based on microbiota-gut-brain axis
Research progress on the effect of α-synuclein in acupuncture treatment for Parkinson’s disease
Advances of researches on acupuncture treatment of Parkinson’s disease by regulating mitochondrial function
Related Author
LIU Yi
ZHOU Meng-di
ZHENG Yu-qi
SUN Ming-sheng
WANG Zi-wen
CAI Ding-jun
ZHAO Ling
WANG Meng-meng
Related Institution
School of Acupuncture and Massage, Chengdu University of Traditional Chinese Medicine
College of Acupuncture-Moxibustion and Tuina,Shandong University of Traditional Chinese Medicine
Department of Acupuncture-moxibustion,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Department of Traditional Chinese Medicine,Shandong Maternal and Child Health Care Hospital
Shandong Provincial Key Laboratory of Traditional Chinese Medicine,the Acupuncture Neurobiology Laboratory