Progress of Studies on Mechanisms of Acupuncture Underlying Regulation of Cardiac Function Via Autonomic Nervous System

WANG Ya-li; YU Zhi; XU Bin

doi:10.13702/j.1000-0607.2014.01.016

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Progress of Studies on Mechanisms of Acupuncture Underlying Regulation of Cardiac Function Via Autonomic Nervous System

更新时间：2023-08-11

- Progress of Studies on Mechanisms of Acupuncture Underlying Regulation of Cardiac Function Via Autonomic Nervous System
- Acupuncture Research Vol. 39, Issue 1, Pages: 83-86(2014)
- 作者机构：
  
  南京中医药大学第二临床医学院针药结合省部共建教育部重点实验室
- 作者简介：
- 基金信息：
- DOI：10.13702/j.1000-0607.2014.01.016
  CLC：
- Published：2014
- 稿件说明：
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WANG Ya-li, YU Zhi, XU Bin. Progress of Studies on Mechanisms of Acupuncture Underlying Regulation of Cardiac Function Via Autonomic Nervous System[J]. Acupuncture research, 2014, 39(1): 83-86.
DOI：

WANG Ya-li, YU Zhi, XU Bin. Progress of Studies on Mechanisms of Acupuncture Underlying Regulation of Cardiac Function Via Autonomic Nervous System[J]. Acupuncture research, 2014, 39(1): 83-86. DOI： 10.13702/j.1000-0607.2014.01.016.

摘要

针刺治疗心血管疾病疗效已经得到临床和基础研究的证实

针刺调节自主神经系统是其关键机制之一。肾上腺素β受体作为心交感神经递质的主要靶受体

心交感神经通过该受体调节心脏的功能。本文从肾上腺素β受体信号通路及交感神经和迷走神经活动的平衡角度出发

对近几年针刺治疗心血管疾病的机制进行梳理

以期为针灸科学化提供参考资料。

Abstract

Acupuncture therapy has been confirmed to be effective in treating cardiovascular diseases in clinical practice.Acupuncture-induced balance of the autonomic nervous system activities is one of its key mechanisms.In the present paper

the authors review progress of studies on acupuncture treatment of cardiovascular diseases from 1)regulating cardiac sympathetic-beta-adrenergic receptor activity and myocardial intracellular GTP-binding protein(Gs)-adenylylcyclase(AC)-cyclic adenosine monophosphate(cAMP)-protein kinase(PKA)signaling

and 2)balancing cardiac sympathetic and vagal nerve activities.Due to limited experimental conditions

in-depth studies about the mechanisms of acupuncture intervention underlying improvement of cardiovascular functions are relatively fewer up to now.Along with the further development of modern biology

the mechanism of acupuncture intervention underlying regulation of cardiac function via autonomic nerve system will be revealed in detail.

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