Long-lasting hypertension results in ventricular remodeling characteristic of myocardial hypertrophy including myocyte hypertrophy and myocardial fibrosis
apathological process failed to be blocked by the current biomedical means and could eventually lead to heart failure.It has been shown that acupuncture can excite the parasympathetic nerve to counter the overtonic activity of sympathetic nerve
elicit antihypertensive effect and produce cardioprotection via the regulation of calcium signaling-related proteins in myocytes
suggesting its potential role in the management of these disorders.In this paper
the authors review relevant studies and propose
with respect to the autonomic nerve
endocrine system
cytokines and intracellular calcium signaling pathways
several novel ideas concerning the treatment of hypertensive myocardial hypertrophy and cardiac malfunction by acupuncture.
Study on the antihypertensive mechanism of acupuncture at “Renying” (ST9) and “Zusanli” (ST36) via gastrin/cholecystokinin B receptors
Progress of researches on mechanisms of acupuncture therapy for lowering blood pressure
New thoughts about study on cholinergic anti-inflammatory pathway in mediating delaying effect of electroacupuncture on myocardial remodeling of chronic hypertension
Our Considerations about Basic Research and Clinical Translation Based on Experimental Studies on Acupuncture-induced Blood-pressure Reduction
Related Author
DING Zhi-min
ZHENG Jie
WANG Hui-ling
CHEN Ting-yu
ZHANG Li-hong
LIU Bin
JIN Xiao-qin
FENG Xiao-dong
Related Institution
School of Rehabilitation Medicine, Henan University of Chinese Medicine
Rehabilitation Center, the First Affiliated Hospital of Henan University of Chinese Medicine
Department of anesthesiology, Peking University People's Hospital
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Key Laboratory for Researching Combination of Acupuncture and Medicines Established by the Ministry of Education and Jiangsu Province,Nanjing University of Chinese Medicine