Objective To observe the clinical therapeutic effect of acupoint injection of medicine in the treatment of patients with acute cerebral ischemia stroke(ACIS).Methods Ninety ACIS patients were randomized into control

Cobalamin and Gangliosides groups(n=30in each group).Patients of the control group were treated by routine medication(i.e.

drugs for improving microcirculation

anti-platelet aggregation

cerebral dehydration

neuronutrition

intracranial pressure reduction and blood lipid-lowering

etc.)and motor function rehabilitation training

once daily

six times a week for two weeks;and those of the Cobalamin and Gangliosides groups were treated by injection of Cobalamin(1mL)or Gangliosides(1mL)into Baihui(GV 20)and Zusanli(ST 36)

respectively and rehabilitation training(being the same to the control group).The patients' motor ability and physical status were assessed according to clinical neurologic deficit score(CNDS)and activity of daily living scale(ADLS).Results After the treatment

of the three 30 cases in the control

Cobalamin and Gangliosides groups

0

4and 2were cured

9

15 and 14experienced marked improvement in their symptoms

12

8and 10 were improved

9

3and 4invalid

with the effective rates being 70.0%(21/30)

90.0%(27/30)and 86.7%(26/30)

respectively.In comparison with pre-treatment

the CNDS of the three groups were all significantly decreased and the ADLS notably increased(P<0.05).The effects of both Cobalamin and Gangliosides were remarkably better than those of the control in lowering CNDS and raising ADLS(P<0.05)

and the score of ADLS in the Cobalamin group was markedly higher than that in the Gangliosides group(P<0.05).Conclusion Acupoint injection of both Cobalamin and Gangliosides can effectively improve acute ischemic stroke patients' neurological function and daily life living ability.