ZHOU Yin, ZHU Jun, LI Lian-bo, et al. Effects of Electroacupuncture on Joint Function in Rheumatoid Arthritis Patients of Liver-and Kidney-Yin Deficiency Type[J]. Acupuncture research, 2016, 41(5): 440-446.
DOI:
ZHOU Yin, ZHU Jun, LI Lian-bo, et al. Effects of Electroacupuncture on Joint Function in Rheumatoid Arthritis Patients of Liver-and Kidney-Yin Deficiency Type[J]. Acupuncture research, 2016, 41(5): 440-446. DOI: 10.13702/j.1000-0607.2016.05.014.
Effects of Electroacupuncture on Joint Function in Rheumatoid Arthritis Patients of Liver-and Kidney-Yin Deficiency Type
Objective To compare the effects between electroacupuncture(EA)plus western medicine and simple western medicine in improving clinical symptoms and local joint function of rheumatoid arthritis(RA)patients with yin deficiency of Liver and Kidney.Methods A total of 68 RA patients of yin deficiency of Liver and Kidney were equally randomized into EA+medication group and medication group(n=34in each group).Both groups were given once-a-week methotrexate(7.5mg/time)and once-a-day leflunomide(10mg/time)
while EA+medication group was additionally treated by EA at bilateral Ganshu(BL 18)
Shenshu(BL 23)
Xuanzhong(GB 39)
Zusanli(ST 36)
Taichong(LR 3)
Hegu(LI 4)3times/week.The treatment lasted for 12 weeks.The visual analogue scale(VAS
for assessing rest pain)
swollen joint count(SJC)
tender joint count(TJC)
patient's global assessment(PGA)
physician's global assessment(PhGA)
traditional Chinese medicine(TCM)symptom scoring
28 joints activity index(disease activity score
DAS 28)
American College of Rheumatology 20(ACR 20
i.e.20% of clinical improving rate)
and health assessment questionnaire(HAQ)were assessed and erythrocyte sedimentation rate(ESR)
serum C-reactive protein(CRP)levels were examined for comparison.Results Statistical differences were observed in before-after-treatment comparisons in both groups in reducing rest pain
SJC
TJC
serum CRP content
PGA and PhGA
HAQ scoring and DAS 28(P<0.05
P<0.01).The ESR in the medication group and TCM symptom scoring of the EA+medication group were also significantly decreased after the treatment(P<0.05).The effects of the EA+medication group were superior to those of the medication group in reducing rest pain
SJC
TJC
TCM symptom and HAQ score
and the total effetive rate(P<0.05
90.9% vs 66.67%).Adverse reactions as pharyngeal obstruction sensation
anorexia
abdominal distension
etc.can be reduced by EA therapy coordinated with western medicine.Conclusion EA is effective in relieving symptom and joint function in RA patients with yin deficiency of Liver and Kidney.