LUO Ya, YAO Dan-ni, LU Chuan-jian. Adverse events/adverse reactions of acupoint catgut embedding therapy for psoriasis vulgaris:a systematic review[J]. Acupuncture research, 2022, 47(4): 369-376.
DOI:
LUO Ya, YAO Dan-ni, LU Chuan-jian. Adverse events/adverse reactions of acupoint catgut embedding therapy for psoriasis vulgaris:a systematic review[J]. Acupuncture research, 2022, 47(4): 369-376. DOI: 10.13702/j.1000-0607.20210077.
Adverse events/adverse reactions of acupoint catgut embedding therapy for psoriasis vulgaris:a systematic review
Objective To systematically review the occurrence of adverse events/adverse reactions(AEs/ARs) induced by acupoint catgut embedding therapy for psoriasis vulgaris(PV) and its safety. Methods Randomized controlled trials
controlled clinical trials
cohort studies
case-control studies
case-series
and case reports concerning the treatment of PV with acupoint catgut embedding therapy were searched from Chinese and English databases from their inception to January 7
(th)
2021. The AEs/ARs related to acupoint catgut embedding therapy for PV were subjected to descriptive statistics
followed by the analysis of possible reasons. Results Finally
16 studies were included
involving 1 158 patients. A total of 79 cases were reported to present with mild to moderate AEs/ARs related to acupoint catgut embedding therapy for PV
and there were no serious AEs/ARs or death cases. The most common AEs/ARs were local redness
swelling
heat
and pain(31.65%
25/79)
followed by low-grade fever and fatigue(29.11%
23/79)
isomorphic reaction(16.46%
13/79)
local induration(13.92%
11/79)
and fainting(8.86%
7/79). In terms of embedding materials
catgut(93.67%
74/79) and lumbar puncture needles or other puncture needles(49.37%
39/79) were proved the most common AEs/ARs-inducing factors. The proportion of AEs/ARs resulting from treatment interval≤two weeks(67.09%
53/79) and treatment course≤eight weeks(55.70%
44/79) was relatively high. Because the incidence of AEs/ARs fails to be calcula-ted
it is not yet possible to accurately assess the risk and safety of acupoint catgut embedding therapy for PV. Conclusion Available evidence suggests that in the treatment of PV
acupoint catgut embedding therapy may induce a series of mild to moderate AEs/ARs
so its clinical practice deserves attention. We should strictly grasp its indications and contraindications
and prevent the occurrence of related AEs/ARs by standardizing the operation and improving the embedding materials.