WEI Yu-ting, ZHU Tian-tian, JIA Jing, et al. Research progress on the mechanism of acupuncture intervention on Alzheimer’s disease[J]. Acupuncture research, 2022, 47(4): 362-368.
DOI:
WEI Yu-ting, ZHU Tian-tian, JIA Jing, et al. Research progress on the mechanism of acupuncture intervention on Alzheimer’s disease[J]. Acupuncture research, 2022, 47(4): 362-368. DOI: 10.13702/j.1000-0607.20210480.
Research progress on the mechanism of acupuncture intervention on Alzheimer’s disease
Alzheimer's disease(AD) is a common neurodegenerative disease in the elderly. Studies have shown that acupuncture can effectively alleviate the symptoms of AD and slow down the disease progression
and its mechanism has been intensively explored. This paper summarized the researches on the mechanism of acupuncture intervention on AD in the past 5 years. It has been found that acupuncture intervention on AD is correlated with the regulation of the expression levels of relevant proteins
the inhibition of central inflammatory response
the resistance to oxidative stress injury
the modulation of brain energy metabolism
the improvement of neuronal synaptic plasticity
the adjustment of autophagy activity and the suppression of neuronal apoptosis.