“Significant progress has been made in the field of arthritis treatment. The research team treated knee osteoarthritis (KOA) and rheumatoid arthritis (RA) rats with moxibustion "Zusanli" and observed in depth the polarization of synovial macrophages in the knee joint. The experimental results showed that moxibustion can effectively reduce knee joint inflammatory injury and regulate inflammatory response in both AKO and RA rats. For; For ARA rats, moxibustion mainly promotes the inhibition of polarization polarization of MM21 macrophages, and increases the level of reducing the content of the inhibitory and pro-inflammatory cytokine ILIL-110 β. This discovery may reveal the targeted regulatory mechanism of the "Zusanli" acupoint on different body states. This study not only provides new ideas for the treatment of arthritis, but also supports the development of acupuncture and moxibustion theory in Chinese medicine. In the future, the potential application of moxibustion in the treatment of arthritis is worth looking forward to.”