Research progress of acupuncture-moxibustion in treatment of spinal cord injury through mediating inflammatory reaction

MEI Ji-lin; YANG Zhi-xin; LI Xiao-ning

doi:10.13702/j.1000-0607.20221181

您当前的位置：

首页 >

文章列表页 >

Research progress of acupuncture-moxibustion in treatment of spinal cord injury through mediating inflammatory reaction

更新时间：2023-08-11

- Research progress of acupuncture-moxibustion in treatment of spinal cord injury through mediating inflammatory reaction
- Acupuncture Research Vol. 48, Issue 7, Pages: 699-705(2023)
- 作者机构：
  
  1. 黑龙江中医药大学
  2. 承德医学院
  3. 黑龙江中医药大学附属第二医院
- 作者简介：
- 基金信息：
- DOI：10.13702/j.1000-0607.20221181
  CLC：
- Published：2023
- 稿件说明：
移动端阅览
MEI Ji-lin, YANG Zhi-xin, LI Xiao-ning. Research progress of acupuncture-moxibustion in treatment of spinal cord injury through mediating inflammatory reaction[J]. Acupuncture research, 2023, 48(7): 699-705.
DOI：

MEI Ji-lin, YANG Zhi-xin, LI Xiao-ning. Research progress of acupuncture-moxibustion in treatment of spinal cord injury through mediating inflammatory reaction[J]. Acupuncture research, 2023, 48(7): 699-705. DOI： 10.13702/j.1000-0607.20221181.

摘要

脊髓损伤(SCI)后炎性反应是神经功能恢复的主要障碍。在SCI的发生发展中，炎性反应涉及多种复杂调节机制，包括巨噬细胞、小胶质细胞等炎性反应细胞激活，肿瘤坏死因子、白细胞介素、趋化因子等细胞因子的释放等。针灸治疗SCI临床疗效显著，其作用机制与调节SCI后炎性反应细胞功能、细胞因子表达、NOD样受体热蛋白结构域相关蛋白3炎性小体的活化、高迁移率族蛋白B1和降钙素基因相关肽的表达有关。本文总结近年来SCI炎性反应的机制研究进展及针灸干预的作用机制，为阐明SCI发病机制及针灸干预作用提供参考。

Abstract

Inflammatory reaction after spinal cord injury(SCI) is the main obstacle to the recovery of neural function. In the occurrence and development of SCI

the complex regulatory mechanisms are involved in inflammatory reaction

including the activation of inflammatory cells(e.g.macrophages and microglia)

and the release of cytokines(e.g. tumor necrosis factor

interleukin and chemokines). Acupuncture-moxibustion is significantly effective in clinical treatment of SCI

and its mechanism is related to adjusting the function of inflammatory cells after SCI

modulating the expression of cytokines and the activation of NLRP3 inflammatory bodies

as well as the expression of high mobility group protein B1 and calcitonin gene related peptide. This article summarizes the research progress of mechanism of inflammatory reaction after SCI and the effects of acupuncture-moxibustion intervention in recent years so that the new ideas can be provided to clarify the pathogenesis of SCI and the effect of acupuncture-moxibustion intervention.

关键词

Keywords

references

Views

508

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Research progress on the mechanisms of acupuncture in improving neurogenic bladder after spinal cord injury

Progress of researches on acupuncture treatment of spinal cord injury by promoting axonal regeneration

Development of Studies on Influence of Patients' Expectations on Therapeutic Effects of Acupuncture and Moxibustion Interventions

Related Author

HUANG Jing

REN Ya-feng

LI Bing

ZHANG Zhi-lan

HUANG Xiao-meng

SHANG Wen-ya

XU Qian

SHI Guang-xia

Related Institution

Henan University of Chinese Medicine

The First Affiliated Hospital of Henan University of Chinese Medicine

Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University

Tianjin University of Chinese Medicine

College of Acupuncture-Moxibustion and Tuina，Shandong University of Traditional Chinese Medicine

Postal code：100700
Tel：010-64089344,84014607 Email：zcyjbjb@vip.163.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05017590号-8 京公网安备11010802020460号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰