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Effect of moxibustion combined with intraperitoneal injection of benazepril on endoplasmic reticulum stress-related protein phosphorylation in rats with chronic heart failure
更新时间:2024-05-09
    • Effect of moxibustion combined with intraperitoneal injection of benazepril on endoplasmic reticulum stress-related protein phosphorylation in rats with chronic heart failure

    • A study on the combination of moxibustion and benazepril in the treatment of chronic heart failure (CHF) has made significant progress. This study replicated a CHF rat model and observed the effects of moxibustion "Xinshu" and "Feishu" combined with benazepril on heart function and key proteins in myocardial tissue. The results showed that moxibustion combined with drug therapy can effectively improve the cardiac function of rats, reduce the levels of B-type brain natriuretic peptide (BNP) and angiotensin II (Ang II) in serum, and decrease the expression of phosphorylated PERK and eIF2 α proteins in myocardial tissue. This discovery provides a scientific basis for the combination of moxibustion and medication in the treatment of CHF, and offers new ideas for future clinical research and application.
    • Acupuncture Research   Vol. 49, Issue 3, Pages: 231-237(2024)
    • DOI:10.13702/j.1000-0607.20221265    

      CLC:
    • Received:11 November 2022

      Revised:23 March 2023

      Published:25 March 2024

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  • WANG Heng,XIA Ran,GAO Bing,et al.Effect of moxibustion combined with intraperitoneal injection of benazepril on endoplasmic reticulum stress-related protein phosphorylation in rats with chronic heart failure[J].Acupuncture Research,2024,49(03):231-237. DOI: 10.13702/j.1000-0607.20221265.

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Related Author

WANG Wei
LI Qing-ling
MA Qiang
XIA Ran
GAO Bing
WANG Yi
WANG Jing
LI Qing-ling

Related Institution

Clinical College of Chinese Medicine,Anhui University of Chinese Medicine
Graduate School, Anhui University of Chinese Medicine
College of Acupuncture and Massage, Anhui University of Chinese Medicine
Center for Xin’an Medicine and Modernization of Traditional Chinese Medicine of IHM,2College of Acupuncture-Moxibustion and Massage, College of Traditional Chinese Medicine, Anhui University of Chinese Medicine
Key Laboratory of Xin’an Medicine, Ministry of Education, Anhui University of Chinese Medicine
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