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Quantitative evaluation of warm acupuncture-moxibustion in improvement of cartilage damage in rabbits with early knee osteoarthritis based on MR T2 mapping
更新时间:2024-05-08
    • Quantitative evaluation of warm acupuncture-moxibustion in improvement of cartilage damage in rabbits with early knee osteoarthritis based on MR T2 mapping

    • In the field of early treatment of knee osteoarthritis (KOA), the research team used magnetic resonance (MR) T2 mapping imaging technology to deeply explore the effect of warm acupuncture and moxibustion on cartilage degeneration and repair in rabbits. The experimental results show that warm acupuncture and moxibustion can significantly reduce the T2 value in the articular cartilage of early KOA rabbits, which is closely related to the reduction of the expression of matrix metalloproteinase-1 (MMP-1) and MMP-13 protein in the extracellular matrix of cartilage. This finding not only confirmed the value of T2 value in evaluating warm acupuncture and moxibustion for repairing early cartilage degeneration in KOA rabbits, but also provided a new research direction and solution in this field. This study not only helps us to gain a deeper understanding of the pathogenesis of KOA, but also provides new ideas and methods for the early treatment of KOA.
    • Acupuncture Research   Vol. 48, Issue 11, Pages: 1117-1124(2023)
    • DOI:10.13702/j.1000-0607.20221433    

      CLC: R245.31+5
    • Received:17 December 2022

      Revised:11 May 2023

      Published:25 November 2023

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  • WANG Ming-lei,LI Chun,LIU Jun-wei,et al.Quantitative evaluation of warm acupuncture-moxibustion in improvement of cartilage damage in rabbits with early knee osteoarthritis based on MR T2 mapping[J].Acupuncture Research,2023,48(11):1117-1124. DOI: 10.13702/j.1000-0607.20221433.

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Related Institution

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