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Guasha improves knee osteoarthritis by inhibiting chondrocyte apoptosis and regulating expression of autophagy-related genes and proteins in rats
更新时间：2024-05-09

    • Guasha improves knee osteoarthritis by inhibiting chondrocyte apoptosis and regulating expression of autophagy-related genes and proteins in rats

    • “Guasha has a significant improvement effect on joint cartilage damage in rats with knee osteoarthritis. Research has found that guasha can inhibit the excessive release of inflammatory factors and reduce the apoptosis rate of chondrocytes. This is attributed to Guasha upregulating the expression of Beclin-1 and LC3, while reducing the expression of P62 and Caspase-3, promoting the autophagy process of chondrocytes. This study provides new scientific basis for the treatment of knee osteoarthritis with guasha, and brings new insights into the field of arthritis treatment.”
    • Acupuncture Research   Vol. 49, Issue 3, Pages: 247-255(2024)

    • DOI：10.13702/j.1000-0607.20230493    

      CLC：

    • Received：11 June 2023，

      Revised：11 October 2023，

      Published：25 March 2024

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  • YAN Xue-hua,ZHU Hao,CHEN Shuai,et al.Guasha improves knee osteoarthritis by inhibiting chondrocyte apoptosis and regulating expression of autophagy-related genes and proteins in rats[J].Acupuncture Research,2024,49(03):247-255. DOI： 10.13702/j.1000-0607.20230493.

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Related Author

ZHOU Xin-hua
YANG Qi-qi
LI Wei-ran
WANG Ke-po
Qiu Shuai-hui
LI Chun-ning
LI Fei
LIU Li

Related Institution

Graduate School， Anhui University of Chinese Medicine
Wuxi Second Hospital of Traditional Chinese Medicine
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The First Affiliated Hospital/The First Clinical College of Hunan University of Chinese Medicine
College of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine
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