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Electroacupuncture improves colonic mucosal barrier damage by regulating NLRP3/Caspase-1/GSDMD signaling pathway and inhibiting pyroptosis in ulcerative colitis mice
更新时间：2025-06-21

    • Electroacupuncture improves colonic mucosal barrier damage by regulating NLRP3/Caspase-1/GSDMD signaling pathway and inhibiting pyroptosis in ulcerative colitis mice

    • “Electroacupuncture of "Tian Shu" and "Zu San Li" can improve symptoms of ulcerative colitis in mice, restore colonic mucosal permeability, and the mechanism involves regulating the NLRP3/Caspase-1/GSDMD axis to inhibit cell pyroptosis and improve intestinal mucosal inflammatory damage.”
    • Acupuncture Research   Vol. 50, Issue 3, Pages: 277-286(2025)

    • DOI：10.13702/j.1000-0607.20240402    

      CLC：

    • Received：25 April 2024，

      Revised：25 September 2024，

      Published：25 March 2025

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  • WANG Xi-han,LIU Ji-dong,QU Yi,et al.Electroacupuncture improves colonic mucosal barrier damage by regulating NLRP3/Caspase-1/GSDMD signaling pathway and inhibiting pyroptosis in ulcerative colitis mice[J].Acupuncture Research,2025,50(03):277-286. DOI： 10.13702/j.1000-0607.20240402.

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