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Effects of acupotomy therapy on macrophage polarization and inhibition of synovial inflammation in rabbits with knee osteoarthritis based on the Notch1/Jagged1/Hes1 signaling pathway
更新时间：2025-06-21

    • Effects of acupotomy therapy on macrophage polarization and inhibition of synovial inflammation in rabbits with knee osteoarthritis based on the Notch1/Jagged1/Hes1 signaling pathway

    • “In the field of knee osteoarthritis treatment, experts use needle knife to release the lesions around the knee meridian muscles, regulate the Notch1/Jagged1/Hes1 signaling pathway, alleviate synovial tissue inflammatory response, regulate macrophage polarization transformation, and provide a new mechanism for treatment.”
    • Acupuncture Research   Vol. 50, Issue 6, Pages: 649-657(2025)

    • DOI：10.13702/j.1000-0607.20240962    

      CLC：

    • Received：22 September 2024，

      Revised：27 November 2024，

      Published：25 June 2025

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  • YU Wen-ying,XIU Zhong-biao,LIN Ze-hao,et al.Effects of acupotomy therapy on macrophage polarization and inhibition of synovial inflammation in rabbits with knee osteoarthritis based on the Notch1/Jagged1/Hes1 signaling pathway[J].Acupuncture Research,2025,50(06):649-657. DOI： 10.13702/j.1000-0607.20240962.

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Related Author

QI Xin
CHEN You-nan
MA Yun-xuan
XING Long-fei
CUI Yong-qi
GUO Chang-qing
WANG Cheng
YUAN Jun

Related Institution

School of Acupuncture-moxibustion and Tuina， Beijing University of Chinese Medicine
College of Acupuncture-Moxibustion and Tuina， Chengdu University of Traditional Chinese Medicine
Graduate School， Anhui University of Chinese Medicine
Department of Acupotomy Rehabilitation， Anhui Hospital of Integrated Traditional Chinese and Western Medicine
The Department of Joint and Bone， Lu’an Hospital of Traditional Chinese Medicine， Lu’an
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