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Electroacupuncture improves senescence of ovarian granulosa cells by regulating P53/P21 signaling pathway in rats with premature ovarian insufficiency
更新时间：2025-12-22

    • Electroacupuncture improves senescence of ovarian granulosa cells by regulating P53/P21 signaling pathway in rats with premature ovarian insufficiency

    • “The latest research has found that electroacupuncture at the "Gongsun" acupoint can regulate the levels of sex hormones in rats with early-onset ovarian dysfunction, slow down the aging of ovarian granulosa cells, and improve fertility, which may be related to the regulation of the P53/P21 pathway.”
    • Acupuncture Research   Vol. 50, Issue 12, Pages: 1440-1448(2025)

    • DOI：10.13702/j.1000-0607.20241116    

      CLC：

    • Received：31 October 2024，

      Revised：2025-02-13，

      Published：25 December 2025

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  • ZHANG Dan-ni,HUANG Si-dan,SHI Xu-liang,et al.Electroacupuncture improves senescence of ovarian granulosa cells by regulating P53/P21 signaling pathway in rats with premature ovarian insufficiency[J].Acupuncture Research,2025,50(12):1440-1448. DOI： 10.13702/j.1000-0607.20241116.

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ZHANG Dan-ni
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SHI Xu-liang
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LI Xin-yue

Related Institution

International Joint Research Center for Predominant Diseases of Traditional Chinese Medicine and Acupuncture of Hebei
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College of Acupuncture-moxibustion and Tuina， Hebei University of Chinese Medicine
Dou Han-qing Academic Thought Research Institute of Hebei University of Chinese Medicine
The First Clinical Medical School of Hunan University of Chinese Medicine
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