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Electroacupuncture improves intestinal motility and visceral sensitivity in mice with functional constipation via up-regulating Piezo1/2 channel activity
更新时间：2026-03-16

    • Electroacupuncture improves intestinal motility and visceral sensitivity in mice with functional constipation via up-regulating Piezo1/2 channel activity

    • “Research has found that electroacupuncture can improve intestinal motility and sensitivity disorders in mice with functional constipation. The mechanism may be through upregulation of Piezo channel expression in intestinal chromaffin cells, promoting Ca2+influx and 5-hydroxytryptamine secretion.”
    • Acupuncture Research   Vol. 51, Issue 3, Pages: 332-340(2026)

    • DOI：10.13702/j.1000-0607.20250172    

      CLC：

    • Received：21 February 2025，

      Revised：2025-04-01，

      Online First：23 September 2025，

      Published：25 March 2026

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  • YAN Xiang-yun,LI Yan-qiu,MA Pei-tao,et al.Electroacupuncture improves intestinal motility and visceral sensitivity in mice with functional constipation via up-regulating Piezo1/2 channel activity[J].Acupuncture Research,2026,51(03):332-340. DOI： 10.13702/j.1000-0607.20250172.

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YAN Xiang-yun
LI Yan-qiu
MA Pei-tao
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HOU Yu-jun
CHEN Ke-duo
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Related Institution

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Key Laboratory of Acupuncture and Moxibustion for the Prevention and Treatment of Geriatric Diseases （Ministry of Education）
Key Laboratory of Acupuncture and Moxibustion for the Prevention and Treatment of Geriatric Diseases （Ministry of Education）
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College of Acupuncture-moxibustion and Tuina, Hebei University of Chinese Medicine
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