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Effects of electroacupuncture on the SIRT3/NF-κB /MAPK signaling pathway in the substantia nigra of mice with Parkinson’s disease
更新时间:2026-03-16
    • Effects of electroacupuncture on the SIRT3/NF-κB /MAPK signaling pathway in the substantia nigra of mice with Parkinson’s disease

    • Electroacupuncture can improve motor dysfunction in PD mice, reduce the loss of dopaminergic neurons in the substantia nigra of the midbrain, and increase TH expression levels. Its mechanism of action may be related to the regulation of the SIRT3/NF - κ B/MAPK signaling pathway to inhibit neuroinflammatory responses
    • Acupuncture Research   Vol. 51, Issue 3, Pages: 294-301(2026)
    • DOI:10.13702/j.1000-0607.20250234    

      CLC:
    • Received:05 March 2025

      Revised:2025-06-19

      Online First:09 December 2025

      Published:25 March 2026

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  • QI Ling,ZHANG Xiao-lei,LI Ya-nan,et al.Effects of electroacupuncture on the SIRT3/NF-κB /MAPK signaling pathway in the substantia nigra of mice with Parkinson’s disease[J].Acupuncture Research,2026,51(03):294-301. DOI: 10.13702/j.1000-0607.20250234.

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Related Author

QI Ling
ZHANG Xiao-Lei
LI Ya-nan
LI Han-Zhang
XIAO Die
TAO Xiao-yi
MA Jun
LU Zhuan

Related Institution

College of Acupuncture-moxibustion and Orthopaedics, Hubei University of Chinese Medicine
Department of acupuncture and moxibustion, Hubei Hospital of Traditional Chinese Medicine
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Zhongjing College of Henan University of Traditional Chinese Medicine
College of Rehabilitation Medicine, Henan University of Traditional Chinese Medicine
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