摘要:Recent research about the role of adrenocorticosteroids in acupuncture analgesia and acupunctureanaesthesia have been reviewed.The relationships between the action of acupuncture as well as stressand the regulating function of the living body have been discussed.
摘要:The present paper is divided into two parts.The nucleus caudatus has been described briefly in the first part.(1) The nervous circuity ofnucleus eaudatus:The pars compacta of substantia nigra contains the cell body of one of the maindopamine(DA) fiber systems,the nigro-striatal pathway,which comes from substantia nigra and goesto the nucleus caudatus.There is a neo-striato-nigra pathway,too,making it possible for caudatumand substantia nigra to influence each other's activity.(2) The link of neurons in caudatum:It has been proposed that in the pathway there is a cholinergic link through which caudate DAterminals influence GABA neruronal activity both in interneurons in caudatus and in descendingGABAergic pathways to the substantia nigra.The inhibitory nervous feedback control of the nigro-striatal DA pathway thus seems to involve the inactivation of cholinergic interneurons in thecaudatus,allowing an increased activity to occur in descending inhibitory GABAergic pathwaysinnervating the DA nerve cells of the substantia nigra.(3) The characteristics of dopamine receptors:The theory of excitation-mediating and inhibition-mediating dopamine receptors has beenintroduced.The histochemical,biological,electrophysiological,pharmacological and functionalcharacteristics of dopaminergic receptors have also been described.It is proposed that the excitation-mediating receptors might be situated before,and the inhibition-mediating receptors,after thesynapses.The second part deals with the relationship between the nucleus caudatus and acupuncture anal-gesia.The experiments suggest that the nucleus caudatus has a powerful action to elevate the painthreshold and strengthen the analgesia effect of acupuncture.But the mechanism of oaudate analgesiais not clear yet.Some studies suggest that the dopaminergic system in the nucleus caudatus has anopposite effect on acupuncture analgesia.
摘要:In 1972,we first introduced acupuncture for intraeardiac surgery with extracoporeal circulationand 230 operations were performed under acupuncture anesthesia up to August 1978.Acupuncture points were selected on the ears and extremities in accordance with the channelsand were divided into ten groups which showed no prominent difference as to their efficiency.The effect of acupuncture anesthesia graded according to the national unified standard wasexcellent in 42 cases(18.3%),good in 117 cases(50.9%),fine in 52 cases(22.7%) and poorin 19 cases(8.2%).A random portion of cases was continuously monitored with a polygraph which recorded EEG,ECG,phlethysmogram,galvanic skin response,EMG and respiratory tracings during major steps ofthe operative procedure.The EEG showed a predominance of a rhythm throughout the operativecourse and in some cases there was sporadic or transient appearance of θ or δ rhythm during thecardiopulmonary bypass,which disappeared after termination of the bypass.The ECG demonstratedauricular or ventricular extrasystoles occasionally in some cases before thecardiopulmonary bypassand supraventricular tachycardia in 1/3 of the cases after the bypass.Phlethysmographie tracing disappeared during the course of the bypass.The appearance of galvanic skin response occurred at any manoeuvre of body such as skindisinfection and skin incision with subsidence or disappearance after thoracotomy.Throughout the operation,there were EMC changes during the incision of skin,splitting of thesternum and suturing up of the skin.Spontaneous respiration was held in most of cases during perfusion and recovered 1-2 minutes after its termination.There was no correlation between theeffect and grading of acupuncture anesthesia and plethysmogram,galvanic skin response,EMG andrespiratory tracing.Respiratory spirometry did not demonstrate marked changes before and afterthoracotomy,as well as preoperatively,and the other parameters of blood gas analysis in a portionof cases showed metabolic acidosis before the start and during the course of the bypass,whichreturned to normal 3 hours after its termination.Finally this paper discusses the effect of acupuncture anesthesia on the central nervous,circulatory and respiratory systems under direct vision intracardiae operations.Measures to increase the analgesic effect of acupuncture anesthesia are also mentioned.
摘要:For the purpose of elucidating the role of cholinergic nervous system in the process ofacupuncture anesthesia,the content of acetylcholine(ACh)and the activity of acetylcholinesterase(ACHE)in different regions of brains of rats were estimated without and after electro-acupunctureinduction.The ACh content was estimated with microbioassay method on frog rectus abdominis.TheAChE activity was determined by Hestrin's colorimetric method.The points needled were“Shuigou”(i.e.“Renzhong”)and “Chengjiang”.The frequency of electric stimulation was 60000/min.The results of experiments showed that the ACh content and the AChE activity were significant-ly in (?)sed in the hypothalamus after the beginning of induction for 30 minutes as comparedwith com(?)nimals.Mean contents of ACh in this region of 42 pairs of rats were 0.350±0.077μg/gm for control and 0.738±0.147 μg/gm for needled rats;the difference was statisticallysignificant(P<0.05).Mean activity of AChE in the hypothalamus of 60 pairs of rats were 24.812+0.464 μ moles/100mg tissue/30 min.(at 37℃)for control and 26.321±0.581 μ molesfor needled animals,(0.05>P>0.02).There were no significant changes in thalamus,caudatenuclei and cerebral cortex.The results suggested that ACh in the hypothalamus might play a role in analgesic and regu-latory effects of acupuncture anesthesia.
Hua Xinbang Zhang Wanwen Qiu Yongchao Gong Yanhua Zhu Lingying
Issue 1, Pages: 70-76(1980)
摘要:Needling effect of various cutaneous parts(“Zusanli”,“Indu”,and ear point “Stomach”)on theelectric discharges in terms of integration numbers of gastric and renal branches of the postgangli-onic sympatho-splanchnic nerve was studied in 67 rabbits under conscious and paralysed conditions.The reslts may be summarized as follows:[1]The effect of acupuncture on the activity of gastric nerve and gastric movement varied withdifferent parts.Needling of “Zusanli” caused a decrease of efferent discharges of gastric nerve and an increase of gastric peristalsis.On needling of “Indu” and ear points no significant changewas observed.Statistical analysis of the integretion numbers of electric discharges showed asignificant variation between the needling effects by these points.