摘要:Current literature of research on the mechanism of action of the cerebral cortex in acupuncture analgesia carried out in China in recent years are briefly reviewed.
Acupuncture anesthesia has been developed on the basis of practical experiences and the Channel-visceral theory of the traditional chinese medicine in treatment of diseases, especially in the relieve of pain.
In clinical practice and experiments some results of electrophysiological and biochemical effect of acupuncture upon the cerebral cortex functional activities are summarized in the present review. Evidence of investigations shows that the cerebral cortex takes part in the process of acupuncture analgesia and plays a certain role in the mechanism of acupuncture analgesia. Further investigation will te made yor the explanation of the mechanism of acupuncture anasthesia.
摘要:For the purpose of understanding the relationship between cholinergic neurotransmitter and the mechanism of acupuncture analgesia, the blood cholinesterase(ChE) activities were estimated before and after acupuncture induction in patients operated under acupuncture anaesthesia and in rats. ChE activity was determined by Hestrin's colorimetric method.
In patients with thyroidectomy and removal of thyroid cysts, "Hegu" (L.I.4) and "Neiguan" (P.6) were needled, whle in those with subtotal gastrectomy Renzhong (Du 26) and Chengjiang(R. 24) were needled. In rats "Shuigou" (i.e. Renzhoug) and Chengjiang were needled. The frequency of electric stimulation applied in thyroid operations was 3,600/min., in subtotal gastrectomy and in rats was 60,000/min.
ChE activity in the veinous blood of 100 patients undergoing thyroid operations and 32 patients subjected to subtotal gastrectomy under acupuncture anaesthesia indicated no significant change after 20 minutes inducction (P>0.05).
There were also no significant differences of blood ChE activity in 24 rats after 30 minutes electro-acupuncture induction in comparison with 24 control animals, and in 20 rats during the rise of pain threshold by acupuncture induction in comparison with 20 control animals.
The results seem to suggest that the peripheral cholinergic transmitter may not play an important role in the mechanism of acupuncture analgesia.