最新刊期
卷 ， 期 1 ， 1984
-
-
-
-
-
-
-
- 摘要：Experiments were made to observe the effect of acupuncture at "Nei- guan" point on acute myocardial infarction induced by the ligation of the left arterior descending coronary artery and to show whether there was relative specificity of "Neiguan" point. Twenty healthy dogs weighing 10～18kg were anesthetized with Intra- venous sodium pentobarbital (30 mg/kg) and ventilated with room air using a SC-1 respirator. Thoracotomy was performed through the left 4th or 5th intercostal space, the pericardium opened, and the heart suspended in a pericardial cradle. A root of the left arterior descending coronary arte- ry's second to third branch (LAD) about 1～2 cm long was isolated. Ele- ctrodes made of cotton were applied on the epicardial surface to record epicardial ECG with points. Epicardial ECG, ECG-Ⅱ lead and artery blood pressure were recorded simultaneously on RM-86 polygraph. The number (NST) of ST segment elevation exceeding 2mv showed the extent of the myocardial ischemic injury area, while the mean(ST) of the ST segment elevation from all 24 points represented the severity of myoca- rdial ischemic injury. It has been reported that the NST and ST values of epicardial ECG after the ligation of the LAD served as the control of one- self and between groups. The experiment was carried out in three groups: a control group and two acupuncture groups using "Neiguan" and "Zusanli" points respectively. The results are summarized below: Of the 20 dogs 6 developed ventricular fibrillation during coronary artery ligation or loosening and reperfusion, and they were not included in the study. 2, 5, 10, 15 minutes after loosening the ligation and following repe- rfusion, the extent and severity of myocardial ischemic injury in the acu- puncture "Neiguan" point group were evidently reduced. The NST and ST values were statistically significant (P<0.05, 0.01, 0.01 and 0.05) as co- mpared with those in the control group, but there was no statistical dif- ference between control and acupuncture "Zusanli" point group. 2, 5, 10, 15 and 30 minutes after loosening the ligation and following reperfusion, the extent (NST) and severity (ST) of myocardial ischemic injury in the acupuncture "Neiguan" point group were reduced and were statistically significant (P<0.01) as compared with those in the acupu- ncture "Zusanli" point group. These results suggested the relative specificity in the effect of acupuncture at "Neiguan" point to reduce the extent and severity of myocardial ischemic injury rather than acupuncture at "Zusanli" point. The effect of acupuncture at "Neiguan" point was probably brought about through the increase of coronary blood flow and blood oxygen sup- ply, and the improvement of the oxygen supply in myocardium.1088|0|0更新时间：2023-08-11
-
-
- 摘要：The study was aimed to further investigate the role of the midbrain central gray (CG) in the. process of acupuncture analgesia. Tail-flick and screaming in response to electrical stimulation of the tail skin were taken as indices of pain response. The experiments consisted of four groups: (1) surgical control, (2) electroacupuncture, (3) electrical stimulation of CG, and, (4) simultaneous use of stimulation of CG and electro-acupu- ncture. The pain threshold in the experimental groups increased significa- ntly after electroacupuncture or/and brain stimulation. The pain threshold value of the fourth group was much greater than the summation of that of the second and the third group. The regions of brain being stimulated to produce analgesia were found to locate in the lateral and ventrolateral po- rtions of the caudal CG. This work indicated that there was a synergic action between the analgesic effects produced by stimulation of CG and electro-acupuncture.879|0|0更新时间：2023-08-11
-
-
- 摘要：We have shown that the effect of acupuncture analgesia (AA) and mo- rphine analgesia could be dose-dependently attenuated by intracerebrove- ntricular (icv) injection of cAMP, and potentiated by cGMP. In the present study dibutyryl derivatives of cAMP or cGMP were injected into the subara- chnoid space of the spinal cord to see their effects on AA. Intrathecal catheterization was performed under ether anesthesia. polye- thylene tube of 0.61 mm o. d. was introduced through foramen magnum into the subarachnoid space, reaching the level of thoracolumbar junction. Measurement of tail-flick latency started 4 h after surgery. No significant fluctuation of tail-flick latency was noticed in a period of 60 min follo- wing the intrathecal administration of 50 μg/10 μl of dbcAMP, 20μg/10 μl of dbcGMP or 10μl of artificial CSF. In electroacupuncture (EA) experiments, rats were given intrathecal injection of CSF, followed 15 min later by a session of EA at Zusanli and Sanyinjiao points (2～15 Hz, with increasing voltage from 1V to 2.5V in 30 min). Tail-flick latency was assessed every 10min. The percentage increases of latency in the 3 measurements during the EA period were ave- raged as the average EA analgesia. One hour later, the EA experiment was repeated with intrathecal injection of dbcAMP instead of CSF. The differe- nce in average EA aualgesia between dbcAMP and CSF sessions in individual animals was taken for statistical analysis. It was shown that EA effect was decreased by 30±7%, 58±12% and 75±12% in groups of rats injected with 12.5, 25 and 50μg of dbcAMP respectively (P<0.01 in each group, n=7～11). On the contrary, an augmentation of AA by 13±7% (p>0.05), 25±10% (p<0.05) and 29±10%±(p<0.05) was observed in groups of rats injected with 10, 20 and 40μg of dbcGMP (n=10～13). The results indicate a marked attenuation of AA by intrathecal injection of dbcAMP and a mo- derate potentiation of AA by dbcGMP. A similar effect on AA was thus shown for cyclic nucleotides both in the brain and in the spinal level.914|0|0更新时间：2023-08-11
-
- Postal code：100700
- Tel：010-64089344,84014607 Email：zcyjbjb@vip.163.com
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05017590号-8
京公网安备11010802020460号 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
0